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dc.contributor.authorNamouchi, Amine
dc.contributor.authorGuellil, Meriam
dc.contributor.authorKersten, Oliver
dc.contributor.authorHänsch, Stephanie
dc.contributor.authorOttoni, Claudio
dc.contributor.authorSchmid, Boris Valentijn
dc.contributor.authorPacciani, Elsa
dc.contributor.authorQuaglia, Luisa
dc.contributor.authorVermunt, Marco
dc.contributor.authorBauer, Egil Lindhart
dc.contributor.authorDerrick, Michael
dc.contributor.authorJensen, Anne Østergaard
dc.contributor.authorKacki, Sacha
dc.contributor.authorCohn Jr., Samuel
dc.contributor.authorStenseth, Nils Christian
dc.contributor.authorBramanti, Barbara
dc.date.accessioned2019-01-22T13:48:55Z
dc.date.available2019-01-22T13:48:55Z
dc.date.created2019-01-07T13:34:20Z
dc.date.issued2018-11
dc.identifier.citationProceedings of the National Academy of Sciences of the United States of America. 2018, 115 (50), E11790-E11797nb_NO
dc.identifier.issn0027-8424
dc.identifier.issn1091-6490
dc.identifier.urihttp://hdl.handle.net/11250/2581810
dc.description.abstractOver the last few years, genomic studies on Yersinia pestis, the causative agent of all known plague epidemics, have considerably increased in numbers, spanning a period of about 5,000 y. Nonetheless, questions concerning historical reservoirs and routes of transmission remain open. Here, we present and describe five genomes from the second half of the 14th century and reconstruct the evolutionary history of Y. pestis by reanalyzing previously published genomes and by building a comprehensive phylogeny focused on strains attributed to the Second Plague Pandemic (14th to 18th century). Corroborated by historical and ecological evidence, the presented phylogeny, which includes our Y. pestis genomes, could support the hypothesis of an entry of plague into Western European ports through distinct waves of introduction during the Medieval Period, possibly by means of fur trade routes, as well as the recirculation of plague within the human population via trade routes and human movement.nb_NO
dc.language.isoengnb_NO
dc.publisherNational Academy of Sciencesnb_NO
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.no*
dc.subjectplaguenb_NO
dc.subjectMedievalnb_NO
dc.subjectancient DNAnb_NO
dc.subjectYersinia pestisnb_NO
dc.subjectSecond Pandemicnb_NO
dc.titleIntegrative approach using Yersinia pestis genomes to revisit the historical landscape of plague during the Medieval Periodnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.rights.holderCopyright © 2018 the Author(s). Published by PNAS.nb_NO
dc.source.pagenumberE11790-E11797nb_NO
dc.source.volume115nb_NO
dc.source.journalProceedings of the National Academy of Sciences of the United States of Americanb_NO
dc.source.issue50nb_NO
dc.identifier.doi10.1073/pnas.1812865115
dc.identifier.cristin1651534
cristin.unitcode7530,43,0,0
cristin.unitnameArkeologiavdelingen
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
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